Assistant Professor of Radiology
The Anderson Lab
Neurobiology of Disease
Neurophysiology of distributed brain networks, brain synchrony, functional connectivity. New fMRI, diffusion tensor, and magnetoencephalography methods for diagnosing and understanding neurological disorders such as multiple sclerosis, autism, and Alzheimer Disease.
Dr. Anderson's lab studies distributed brain networks using functional imaging techniques such as fMRI, diffusion tensor imaging, and MEG. A primary emphasis is to develop methods for studying brain synchrony and functional connectivity, and apply these techniques to diagnose neurological and psychiatric disorders of the brain. A few of the ongoing imaging projects in his laboratory include:
- Using fMRI to study functional connectivity abnormalities in multiple sclerosis
- Studying the neurophysiology of visual attention and how imagery and attention are represented in the visual cortex
- Applying techniques of fMRI and MEG to decipher the neural mechanism for synchrony of brain noise in distributed neural networks
- Testing a hypothesis that language disturbances in autism are caused by failure to suppress less important stimuli
- Mapping the visual cortex using imagery in blind patients to identify targets for cortical implants
- Evaluating changes in network connectivity in Alzheimer Disease and aging
- Adapting functional connectivity MRI techniques to study neurophysiology of meditation, yoga, and transcendent experiences
Anderson, J.S., Ferguson, M.A., Lopez-Larson, M., and Yurgelun-Todd, D. (2011) Reproducibility of Single-Subject Functional Connectivity Measurements. Am J Neuroradiol, in press.
Anderson, J.S., Dhatt, H., Ferguson, M.A., Lopez-Larson, M., Schrock, L.A., House, P., and Yurgelun-Todd, D. (2011) Functional Connectivity Targeting for Deep Brain Stimulation in Essential Tremor. Am J Neuroradiol, in press.
Anderson, J.S., Druzgal, T.J., Lopez-Larson, M., and Yurgelun-Todd, D. (2011) Network anticorrelations, global regression, and phase-shifted soft tissue correction. Human Brain Mapping, 32(6):919-934.
Lopez-Larson, M., Anderson, J.S., Ferguson, M.A., and Yurgelun-Todd, D. (2011) Local brain connectivity and associations with gender and age. Developmental Cognitive Neuroscience, 1(2):187-197.
Anderson, J.S., Ferguson, M.A., Lopez-Larson, M., and Yurgelun-Todd, D. (2010) Topographic maps of multisensory attention. PNAS, 107(46):20110-20114.
Anderson, J.S., and Druzgal, T.J., et al. (2010) Decreased interhemispheric connectivity in autism. Cerebral Cortex, (Published online 12 October, 2010).
Anderson, J.S., Druzgal, T.J., Lopez-Larson, M., Jeong, E.K., Desai, K., and Yurgelun-Todd, D. (2010) Network Anticorrelations, Global Regression and Phase Shifted Soft Tissue Correction. Human Brain Mapping, (Published Online Jun 2010).
Shah, L.M., Anderson, J.S., Lee, J.N., and Wiggins, R. (2010) Functional Magnetic Resonance Imaging. Semin. Roent., 45:147-156.
Komakula, S.T., Burr, R.B., Lee, J.N., and Anderson J.S. (2010) Opposite Cerebral Dominance for Reading and Sign Language. Journal of Radiology Case Reports, 4(5):11-14.
Anderson, J.S. (2008) Origin of Synchronized Low-Frequency BOLD Fluctuations in Primary Visual Cortex. American Journal of Neuroradiology, 29:1722-1729.
Gillespie, D.C., Lampl, I., Anderson, J.S., and Ferster D. (2001) Dynamics of the orientation-tuned membrane potential response in cat primary visual cortex. Nature Neuroscience, 4(10):1014-1019.
Lampl, I., Anderson, J.S., Gillespie, D.C., and Ferster, D. (2001) Prediction of orientation selectivity from receptive field architecture in simple cells of cat visual cortex. Neuron, 30(1):263-274.
Anderson, J.S., Lampl, I., Gillespie, D.C., and Ferster, D. (2001) Membrane potential and conductance changes underlying length tuning of cells in cat primary visual cortex. Journal of Neuroscience, 21(6):2104-2112.
Anderson, J.S., Lampl, I., Gillespie, D.C., and Ferster, D. (2000) The contribution of noise to contrast invariance of orientation tuning in cat visual cortex. Science, 290(5498):1968-1972.
Anderson, J.S., Lampl, I., Reichova, I., Carandini, M., and Ferster, D. (2000) Membrane potential fluctuations in the visual responses of complex cells of cat visual cortex. Nature Neuroscience, 3:617-621.
Anderson, J.S., Carandini, M., and Ferster, D. (2000) Orientation tuning of input conductance, excitation, and inhibition in cat primary visual cortex. Journal of Neurophysiology, 84(2):909-926.
Anderson, J.S., Gorey, M.T., Pasternak, J.F., and Trommer, B.L. (1999) Joubert's syndrome and prenatal hydrocephalus. Pediatric Neurology, 20(5):403-405.