Assistant Professor of Bioengineering|
Adjunct Assistant Professor of Ophthalmology & Visual Science
The Greger Lab
Brain and Behavior
Neurobiology of Disease
B.A. 1994, Washington State; B.S. 1995, Washington State University; Ph.D. 2001, Washington University in St. Louis; Postdoctoral Fellow, 2005, Caltech.
Systems level physiology & Neural prostheses
Research in the Greger lab focuses on understanding how information is encoded in neural structures and on how to apply this understanding to the treatment of human pathology. Electrophysiological recordings and electrical micro-stimulation are used to gain an understanding of how the nervous system processes information related to various sensory, motor, and cognitive functions. The results of these experiments are then used to guide implementation of neural prostheses for human patients. Neural prostheses for artificial vision in the profoundly blind, and for decoding speech and movement in the severely paralyzed, are being developed. Electrophysiological research in humans aimed at understanding and treating epilepsy is also ongoing in the lab.
Kellis, S.S., House, P.A., Thomson, K.E., Brown, R., and Greger, B. (2009) Human Neocortical Electrical Activity Recorded on Non-penetrating Microwire Arrays: Applicability for Neuroprostheses, Neurosurgical Focus, Jul;27(1):E9.
Lehmkuhle, M.J., Thomson, K.E., Scheerlinck, P., Pouliot, W., Greger, B., and Dudek, F.E. (2009) A simple quantitative method for analyzing electrographic status epilepticus in rats. Journal of Neurophysiology, Mar;101(3):1660-1670.
Baker, J.J., Yatsenko, D., Schorsch, J., DeMichele, G.A., Troyk, P.R., Hutchinson, D.T., Weir, R., Clark, G., and Greger, B. (2008) Decoding Individuated Finger Flexions Wirelessly with Implantable MyoElectric Sensors. Proceedings of the IEEE Engineering in Medicine and Biology, 2008:193-196.
Norris, S. A., Greger, B., Hathaway, E. N., and Thach, W. (2004) Purkinje cell spike firing in the posterolateral cerebellum: correlation with visual stimulus, oculomotor response, and error feedback. J Neurophysiol, Sep; 92(3):1867-1879.
Musallam, S., Corneil, B. D., Greger, B., Scherberger, H., and Andersen, R. (2004) Cognitive control signals for neural prosthetics. Science, Jul 9; 305(5681):258-262.
Greger, B., Norris, S. A., and Thach, W. (2004) Spike firing in the lateral cerebellar cortex correlated with movement and motor parameters irrespective of the effector limb. J Neurophysiol, Jan; 91(1):576-582.
Martin, T. A., Norris, S. A., Greger, B. E., and Thach, W. (2002) Dynamic coordination of body parts during prism adaptation. J Neurophysiol Oct; 88(4):1685-1694.