GHOLSON J. LYON
Gholson Lyon
email: gholson.lyon@hsc.utah.edu		 Assistant Professor of Psychiatry
Adjunct Assistant Professor of Child and Adolescent Psychiatry, NYU Child Study Center in New York City

Neurobiology of Disease
Brain and Behavior
Molecular Neuroscience

B.A. 1996, Dartmouth College; Ph.D. 2003, Rockefeller University; M.D. 2004, Weill Cornell Medical College. 2004-2005 Internship, Columbia Presbyterian Hospital; 2005-007, Residency, Columbia Presbyterian Hospital and New York State Psychiatric Institute; 2007-2009, Residency, NYU Child Study Center, Bellevue Hospital, and Rockland Children's Hospital

RESEARCH:

Neurobiology of Tourette Syndrome, OCD and ADHD

Dr. Lyon is currently conducting research related to the genetics, pathophysiology, and treatment of Tourette Syndrome, OCD and ADHD. He is also interested in the genetic basis of developmental disabilities such as autism and mental retardation. Research participants are being actively recruited for the above studies, and the people to contact for these studies are Jubel Morgan at office phone 801-587-3775, cell phone 801-678-5634 or email Jubel.Morgan@hsc.utah.edu, or Jennifer Holbrook at 801-585-1212.

Dr. Lyon completed his undergraduate education at Dartmouth College, where he studied biochemistry and molecular biology. He received an M.Phil. in genetics from the University of Cambridge, England and a Ph.D. in pharmacology and peptide chemistry at Rockefeller University. He received his M.D. from Weill Cornell Medical College, followed by adult psychiatry training at the New York State Psychiatric Institute/New York Presbyterian Hospital - Columbia. It was during residency that he became interested in the genetic and pathophysiological basis of many neuropsychiatric disorders, including attention deficit hyperactivity disorder (ADHD), obsessive compulsive disorder (OCD), Tourette Syndrome (TS), schizophrenia and autism. Dr. Lyon subsequently undertook child and adolescent residency at the NYU Child Study Center, during which time he became interested in clinical trials and treatment development for TS, OCD and ADHD. He trained with Dr. Barbara Coffey at NYU, an internationally-recognized specialist in Tourette Syndrome.

Dr. Lyon is currently a member of Phi Beta Kappa, the American Academy of Child and Adolescent Psychiatry, the American Psychiatric Association, the American Neuropsychiatric Association, and the American Association for the Advancement of Science. He has published in the areas of clinical trials, biochemistry, pharmacology, and molecular biology.

Selected Publications

Original Reports

Lyon, G.J., Samar, S., Jummani, R., Hirsch, S., Spirgel, A., Goldman, R., and Coffey, B.J. (2009) Aripiprazole in children and adolescents with Tourette's Disorder: An open label safety and tolerability study. J Child Adolesc Psychopharmacol, (manuscript accepted).

Lyon, G.J., Coffey, B. (2009) Complex tics and complex management in a case of severe Tourette's disorder in an adolescent. J Child Adolesc Psychopharmacol,Aug;19(4):469-474.

Lyon, G.J. (2008) Varenicline-induced paranoia and irritability in a patient with major depressive disorder, borderline personality disorder (stable), and methamphetamine abuse(in remission). J Clin Psychopharmacol, Dec;28(6):720-721.

Lyon, G.J., Coffey, B., and Silva, R. (2008) Post-traumatic stress disorder (PTSD) and Reactive Attachment Disorder: Outcome in an Adolescent. J Child Adolesc Psychopharmacol, Dec;18(6):641-646.

Reviews, Essays, Books, Book Chapters, Book Reviews

Lyon, G.J. and Koplewicz, H.S. (2007) Schizophrenia in childhood: Why we need much more research into early-onset psychosis. SCIENTIST : 22-25 Schizophrenia Suppl. (DEC).

Lyon, G.J. and Coffey, B. (2008) Book Review of: Treating Tourette Syndrome and Tic Disorders: A Guide for Practitioners. Douglas W. Woods, John .C. Piacentini, and John T. Walkup, 2007, First Edition, The Guilford Press, New York. xvi, 287 pages. Hard cover. J Child Adolesc Psychopharmacol. Aug;18(4):411-412.

Lyon, G.J. and Coffey, B. (2008) Book Review of: Attention-Deficit Hyperactivity Disorder: A Handbook for Diagnosis and Treatment. Russell A. Barkley, 2006, Third Edition, The Guilford Press, New York. xii, 770 pages. Hard cover. Journal of Clinical Psychiatry, vol 69, no. 6, (June), p. 1023.

Lyon, G.J., Moore, H., Lieberman, J.A., Abi-Dargham, A., Javitch, J. and Sulzer, D., (2009) Presynaptic regulation of dopamine transmission in schizophrenia. Schizophrenia Bulletin. Jun 12. [Epub ahead of print]

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